Indication

ZELTASIA is indicated for the treatment of adults with relapsing forms of multiple sclerosis (MS).

For adults with relapsing multiple sclerosis (MS) For US Audiences Only
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WHAT DOES IT COST
to take ZELTASIA?

Generally, your out-of-pocket costs related to taking ZELTASIA are determined by your insurance coverage and benefits such as deductibles and co-insurance. This information is intended to help you understand the costs of ZELTASIA.

For your medication:

  • The list price for a 30-day supply of ZELTASIA is $XX. On average, people pay $XX per month
  • A co-pay savings offer is available to eligible patients

For medical costs:

  • You may be eligible for reimbursement of out-of-pocket medical costs associated with getting started with ZELTASIA

Your MS Nurse Navigator can help you better understand your costs and what financial support options are available to you.

Which type of insurance
coverage do you have?

This type of insurance is usually provided by an employer or a union, or purchased directly from an insurance company.

ZELTASIA prescription costs:

On average, patients with this type of insurance pay $XX per month.

Your out-of-pocket cost for ZELTASIA will be determined by your insurance provider, and your MS Nurse Navigator and a team of experts can help you understand what that cost will be (and if you’re eligible for the $0 co-pay offer.*)

The $0 co-pay offer*

Eligible patients may pay as little
as $0 a month for ZELTASIA.

Request co-pay offer

Costs for tests before treatment*:

Before starting ZELTASIA, you may have three medical tests that can be done at a doctor’s office or at your home (in most states)†:

  • An electrocardiogram (ECG)
  • Standard blood tests
  • An eye exam

People with certain preexisting heart conditions, will also have an appointment to take their first dose, where a medical professional will monitor their heart rate.

Your costs may depend on where these tests take place. But for eligible patients, these costs may be reimbursed by the Support Program.

How will you be reimbursed?
If you accrue any costs associated with office visits (co-pay) or routine medical tests when starting ZELTASIA, here’s what to do:

  1. Save all the receipts related to the cost of your office visits, routine medical tests when starting treatment, and first dose appointment (if applicable)
  2. Save your Explanation of Benefits (EOB) form from your insurance carrier (it will be mailed or e-mailed to you)

  3. Submit all receipts and Explanation of Benefits to:

    PATIENT REBATE
    P.O. BOX 1
    PHOENIX, AZ 85069

  4. You’ll receive a check in the mail reimbursing you for what you paid (if eligible)

Ask an MS Nurse Navigator

1-833-ZELTASIA (833-555-5555)
Monday to Friday, 8 am to 8 pm ET

*Depending on insurance coverage and where the full cost is not covered by patient’s insurance, eligible patients may receive a prescription benefit offer for out-of-pocket drug costs and pay as little as $0 per prescription, as well as a medical assessment benefit offer for out-of-pocket costs for the initial blood tests, ECG screening and first-dose observation. Maximum savings limit applies; patient out-of-pocket expenses may vary. This program is not health insurance. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state health care programs. Please click here for Program Terms, Conditions, and Eligibility Criteria.

†Home visits for first dose appointments and routine medical tests are not available to people living in Massachusetts, Michigan, Minnesota, and Rhode Island.

These are government-sponsored health insurance programs.

ZELTASIA prescription costs:

If you have Medicare

People who have prescription insurance through Medicare pay, on average, $XX per month for ZELTASIA.

Low-income subsidy patients may pay $XX to $XX per month through the Social Security Administration’s Extra Help program. Use this link to learn more about Extra Help.

Your out-of-pocket cost for ZELTASIA is determined by your insurance provider. To find out what your costs may be, please call your MS Nurse Navigator (information below).

If you have Medicaid

People with Medicaid pay, on average, $XX per month for ZELTASIA. To find out if you qualify for Medicaid, or to get more information about co-payments in your state, please visit the Medicaid website.

If you need assistance with out-of-pocket costs, your MS Nurse Navigator can help by identifying co-pay assistance foundations that may be able to assist with treatment costs and/or getting access to ZELTASIA.

Ask an MS Nurse Navigator

1-833-ZELTASIA (833-555-5555)
Monday to Friday, 8 am to 8 pm ET

Costs for tests before treatment*:

Before starting ZELTASIA, you may have three routine medical tests that can be done at your home† or at a doctor’s office:

  • An electrocardiogram (ECG)
  • Standard blood tests
  • An eye exam

People with certain preexisting heart conditions, will also have an appointment to take their first dose, where a medical professional will monitor their heart rate.

Regardless of where these appointments take place, you will pay what you normally would for an in-network office visit and/or tests.

*Depending on insurance coverage, eligible patients may receive a medical assessment benefit offer for out-of-pocket costs for the initial blood tests, ECG screening and first-dose observation, where the full cost is not covered by patient’s insurance. Maximum savings limit applies; patient out-of-pocket expenses may vary. This program is not health insurance. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state health care programs. Please click here for Program Terms, Conditions, and Eligibility Criteria.

†Home visits for first dose appointments and routine medical tests are not available to people living in Massachusetts, Michigan, Minnesota, and Rhode Island.

This means you do not have health insurance or your insurance doesn’t cover treatment with ZELTASIA.

If you do not have prescription drug coverage or your insurance does not cover ZELTASIA, you can expect to pay the list price for ZELTASIA of $XXX per month, with any additional pharmacy charges or discounts based on where you purchase your medicine.

If you’re uninsured or underinsured, and need assistance with co-pay or ZELTASIA treatment costs, please reach out to an MS Nurse Navigator to learn about the options available to you.

Ask an MS Nurse Navigator

1-833-ZELTASIA (833-555-5555)
Monday to Friday, 8 am to 8 pm ET

Other areas to explore:

  • Is ZELTASIA effective?

    See how it performed vs a leading injectable medicine (Avonex)* in two separate clinical studies.

    See study results

    *Avonex (interferon beta-1a).

  • Support Program

    Our support program is with you every step of the way with a dedicated MS Nurse Navigator, financial and insurance assistance, and more.

    How we can help

Do not start ZELTASIA if you:

  • Have had a heart attack, chest pain (also known as unstable angina), stroke or mini-stroke (also known as transient ischemic attack or TIA) or certain types of heart failure in the last 6 months
  • Have a history or presence of certain types of irregular or abnormal heartbeat (also known as arrhythmia) that is not corrected by a pacemaker
  • Have severe breathing problems during your sleep (also known as sleep apnea)
  • Are allergic to litifimod or any of the ingredients in ZELTASIA

ZELTASIA may cause serious side effects, including:

  • Slow heart rate (also known as bradycardia) when you start taking ZELTASIA. ZELTASIA can cause your heart rate to temporarily slow down, especially after you take your initial dose. Slow heart rate may occur if you restart ZELTASIA after missing more than 14 consecutive days of treatment. Prior to restarting ZELTASIA, please consult with your physician as you will need a new 7-day starter pack to minimize the risk of heart rate reductions.
    Call your healthcare provider if you experience the following symptoms of slow heart rate such as:
    • Dizziness
    • Shortness of breath
    • Lightheadedness
    • Confusion
    • Feeling like your heart is beating slowly or skipping beats
    • Chest pain
  • Infections. ZELTASIA can increase the risk of infections. You should not receive live vaccines during treatment with ZELTASIA and for 3 months after you stop taking ZELTASIA. Vaccines may not work as well when given during treatment with ZELTASIA. ZELTASIA lowers the number of lymphocytes (a type of white blood cell) and this may lower the ability of your immune system to fight infections. This will usually go back to normal within 3 months of stopping treatment. Your health care provider should review a recent blood test of your white blood cells before you start taking ZELTASIA.
    Call your health care provider right away if you have any of these symptoms of an infection during treatment with ZELTASIA and for 3 months after your last dose of ZELTASIA:
    • Fever
    • Cough
    • Feeling very tired
    • Urinary discomfort
    • Flu-like symptoms
    • Rash
  • Progressive multifocal leukoencephalopathy (PML). Although no cases have been seen in patients in clinical trials with ZELTASIA, PML may occur. PML is a rare brain infection that may lead to death or severe disability. If PML happens, it usually happens in people with weakened immune systems but has happened in people who do not have weakened immune systems. Call your healthcare provider right away if you experience any new or worsening symptoms of PML such as:
    • Weakness on one side of the body
    • Changes in vision
    • Changes in thinking or memory
    • Confusion
    • Personality changes
  • A problem with your vision called macular edema. Macular edema can cause some of the same vision symptoms as a multiple sclerosis (MS) attack (also known as “optic neuritis”). Tell your healthcare provider any time you notice vision changes during treatment with ZELTASIA. Your risk of macular edema is higher if you have diabetes or have had an inflammation of your eye called uveitis. Call your healthcare provider right away if you have any of the following:
    • Blurriness or shadows in the center of your vision
    • A blind spot in the center of your vision
    • Sensitivity to light
    • Unusually colored vision

Before taking ZELTASIA, tell your healthcare provider about all of your medical conditions, including if you:

  • Have liver problems
  • Have a slow heart rate
  • Have a fever or infection
  • Are unable to fight infections due to a disease, or you take or have taken medicines that lower your immune system
  • Have received a vaccine in the past 30 days or are scheduled to receive a vaccine. ZELTASIA may cause vaccines to be less effective
  • Have macular edema or have risk factors for macular edema such as uveitis which is a type of (an inflammation of the eye) or diabetes
  • Are pregnant or plan to become pregnant.
    • If you are a female who can become pregnant, you should use effective birth control during your treatment with ZELTASIA and for at least 3 months after you stop taking ZELTASIA
  • Are breastfeeding or plan to breastfeed.
    • It is not known if ZELTASIA passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby if you take ZELTASIA, are breastfeeding, or plan to breastfeed

Tell your healthcare provider about all the medicines you take or have recently taken, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take or have taken medicines that affect your immune system, including corticosteroids, or other treatments for multiple sclerosis. Know the medicines you take. Keep a list of your medicines with you to show your healthcare provider and pharmacist when you get a new medicine.

ZELTASIA cause possible side effects, including:

  • Swelling and narrowing of the blood vessels in your brain. A condition called PRES (Posterior Reversible Encephalopathy Syndrome) has happened rarely in adults taking ZELTASIA. It is not known if ZELTASIA caused this. ZELTASIA should be stopped if this condition occurs. PRES will usually get better. However, if left untreated, it may lead to a stroke. Call your healthcare provider right away if you have any of the following symptoms:
    • Sudden severe headache
    • Sudden confusion
    • Sudden loss of vision or other changes in your vision
  • Increased blood pressure. Your healthcare provider should check your blood pressure during treatment with ZELTASIA
  • Fetal risk. It is not known if ZELTASIA can cause abnormalities of the fetus. You should use effective birth control during your treatment with ZELTASIA and for at least 3 months after you stop taking ZELTASIA. Call your healthcare provider if you think you may be pregnant [See “What should I tell my healthcare provider before taking ZELTASIA?”]
  • Allergic reactions. Call your healthcare provider if you have symptoms of an allergic reaction, including a rash, itchy hives, or swelling of the lips, tongue or face

The most common side effects of ZELTASIA can include:

  • Colds and sore throat
  • Abnormal liver tests
  • Urinary tract infections
  • High blood pressure (hypertension)
  • Upper respiratory tract infections

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all of the possible side effects of ZELTASIA. For more information, ask your healthcare provider or pharmacist.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information, including Patient Information (Medication Guide)